If pneumonitis management results in complete clinical and radiologic resolution, patients may be able to restart their immune checkpoint inhibitor therapy. Patients who clinically improve with steroid treatment must be monitored closely in the outpatient setting.
In the majority of patients who develop this toxicity, pneumonitis appears to clinically resolve with corticosteroid therapy alone however, a subset of patients require additional immunosuppressive medications.
Herein we discuss two patients who developed pneumonitis secondary to anti-PD-1/PD-L1 immune checkpoint inhibitor therapy and illustrate a stepwise approach to the diagnostic evaluation and management of anti-PD-1/PD-L1-related pneumonitis. His father Suresh is a retired Subehdar in the Communication department of the army and his mother Anila Das is a retired tahsildar.Pneumonitis is defined as a focal or diffuse inflammation of the lung parenchyma, and is a known, potentially fatal toxicity of anti-programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) immune checkpoint inhibitors. He studied in St Aloysius Senior Higher Secondary school till the 12th standard and then pursued graduation in Economics and later B.Tech from Musaliar college of Engineering in Pathanapuram. The accident happened while he was waiting for the final result of the examination for SI in the Delhi police. He was posted as an ASP battalion constable in Thiruvananthapuram. Soon Balu’s father Suresh and relatives headed to Thiruvananthapuram.īalu, who joined the Kerala Police in January 2021 completed his training in September. The people came to know about the mishap through the news channels while his family was informed about the death by his colleagues on Saturday. His family and natives are still in shock. Ambalapuzha: Destiny played a cruel game with Punnapra native Balu, the policeman who died after the boat in which he was travelling capsized on a lake in Anchuthengu.
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